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Constipation was the most frequent complaint2Other adverse effects reported in less than 0.5of the patients are listed below by body system:

These observations suggest that sucralfate’s antiulcer activity is the result of formation of an ulcer-adherent complex that covers the ulcer site and protects it against further attack by acidpepsinand bile saltsThere are approximately 14 to 16 mEq of acid-neutralizing capacity per 1 g dose of sucralfate.

This list is not complete and other drugs may interact with sucralfateTell your doctor about all medications you useThis includes prescriptionover-the-countervitaminand herbal productsDo not start a new medication without telling your doctor.

Duodenal ulcer is a chronicrecurrent diseaseWhile short-term treatment with sucralfate can result in complete healing of the ulcera successful course of treatment with sucralfate should not be expected to alter the post healing frequency or severity of duodenal ulceration.

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